The Recombinant ERCC1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C151140) against ERCC1. Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for IHC applications. It has been validated by IHC analysis of Mouse colon, Rat colon, Human colon cancer, Human lung squamous carcinoma. The target is localized to the nucleus.
Product Name:
Recombinant ERCC1 Monoclonal Antibody
SKU:
AGEL6446
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
COFS 4, COFS4, DNA excision repair protein ERCC 1, DNA excision repair protein ERCC-1, DNA excision repair protein ERCC1, endonuclease non-catalytic subunit, Ercc, ERCC 1, ERCC excision repair 1, ERCC1, Excision repair cross complementation group 1, Excision repair cross complementing 1, Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1, excision repair cross-complementation group 1, Excision repair protein, RAD 10, RAD10, UV 20, UV20
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant human ERCC1 fragment
Applications:
IHC
Clonality:
Recombinant Monoclonal
Clone No:
C151140
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
ERCC1
Conjugation:
Unconjugated
Recommended Dilution:
IHC 1:200-1000
UniProt:
P07992
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.