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Key Features

Recombinant Estrogen Receptor alpha Monoclonal Antibody (AGEL8558)

Datasheet MSDS
SKU AGEL8558
Product Type Antibody
Reactivity Human
Applications WB, IHC-P, IF
Host Species Rabbit
Clonality Monoclonal
Clone C313253
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant Estrogen Receptor alpha Monoclonal Antibody

The Recombinant Estrogen Receptor alpha Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C313253) against Estrogen Receptor alpha. This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB, IHC-P and IF applications. It has been validated by WB analysis of K562, Hela and IF analysis of Human breast cancer, MCF-7. The target is localized to the Nucleus. Cytoplasm. Cell membrane. A minor fraction is associated with the inner membrane and Nucleus. Cytoplasm. Cell membrane. Associated with the inner membrane via palmitoylation.

Product Name:Recombinant Estrogen Receptor alpha Monoclonal Antibody
SKU:AGEL8558
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:4, 5, 6, 7, 7*, 7*/654 isoform, 7*/819 2 isoform, 7*/822 isoform, 8*/901 isoform, 8*/941 isof, 8*/941 isoform, DKFZp686N23123, ER, ER alpha, ER-alpha, Era, ESR, ESR1, ESRA, Estradiol receptor, Estrogen nuclear receptor alpha, Estrogen receptor, Estrogen receptor 1, Estrogen receptor alpha, Estrogen receptor alpha 3*, Estrogen receptor alpha delta 3*, Estrogen receptor alpha delta 4 +49 isoform, Estrogen receptor alpha delta 4*, Estrogen receptor alpha E1 E2 1 2, Estrogen receptor alpha E1 N2 E2 1 2, ESTRR, NR3A1, Nuclear receptor subfamily 3 group A member 1
Reactivity:Human
Immunogen:A synthetic peptide of human Estrogen Receptor alpha
Applications:WBIHC-PIF
Clonality:Recombinant Monoclonal
Clone No:C313253
Host:Rabbit
Isotype:Rabbit IgG
Target:Estrogen Receptor alpha
Conjugation:Unconjugated
Observed MW:66 kDa
Calculated MW:66 kDa
Recommended Dilution:WB 1:500-1000; IHC 1:50-100; IF 1:20-100
UniProt:P03372
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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