The Recombinant FOXC1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331568) against FOXC1. FoxC1, also named as FKHL7 or FREAC3, is one of two mammalian FoxC subfamily members. Along with FoxC2, it is expressed in paraxial mesoderm where it functions to promote somitogenesis, myogenesis, and vascular development, possibly under Wnt/β-catenin regulation. Mutations in FoxC1 are implicated in anterior segment dysgenesis (ASD) disorders, including congenital glaucoma and Axenfeld-Rieger syndrome. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of 293T, MDA-MB-231. The target is localized to the nucleus.
Product Name:
Recombinant FOXC1 Monoclonal Antibody
SKU:
AGEL6873
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
ARA, ASGD, ASGD3, FKH L7, FKHL, FKHL 7, FKHL7, Forkhead (Drosophila) like 7, Forkhead box C1, Forkhead box protein C1, Forkhead drosophila homolog like 7, Forkhead like 7, Forkhead related activator 3, Forkhead related protein FKHL7, Forkhead related transcription factor 3, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3, FOX C1, FOXC, FOXC 1, FOXC1, FREAC 3, FREAC-3, FREAC3, IGDA, IHG, IHG 1, IHG1, IRID, IRID 1, IRID1, Iridogoniodysgenesis type 1, Myeloid factor delta, RIEG, RIEG3
Reactivity:
Human
Immunogen:
Recombinant human FOXC1 fragment
Applications:
WB
Clonality:
Recombinant Monoclonal
Clone No:
C331568
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
FOXC1
Conjugation:
Unconjugated
Observed MW:
70 kDa
Calculated MW:
70-74 kDa
Recommended Dilution:
WB 1:1000
UniProt:
Q12948
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.