The Recombinant Gelsolin Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C371446) against Gelsolin. Gelsolin shares structural and functional homology to villin and adseverin/scinderin. It plays an important role in actin filament assembly by capping and severing actin proteins in a Ca2+-dependent manner. Gelsolin is important for cellular events that require cytoskeletal remodeling. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IF and FCM applications. It has been validated by WB analysis of Human plasma, IF analysis of HeLa, MCF-7 and FCM analysis of HL-60. The target is localized to the cytoplasm.