The Recombinant Glut1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110748) against Glut1. This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of HepG2. The target is localized to the cell membrane, multi-pass membrane protein, melanosome, photoreceptor inner segment, Localizes primarily at the cell surface (PubMed:18245775, PubMed:19449892, PubMed:23219802, PubMed:25982116, PubMed:24847886). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065).
Product Name:
Recombinant Glut1 Monoclonal Antibody
SKU:
AGEL6056
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity), CSE, DYT, DYT17, DYT18, DYT9, EIG, EIG12, erythrocyte/brain, Erythrocyte/hepatoma glucose transporter, facilitated glucose transporter member 1, Glucose transporter 1, Glucose transporter type 1, GLUT, GLUT-1, GLUT1, GLUT1DS, GLUTB, GT1, GTG1, Gtg3, GTR1, HepG2 glucose transporter, HTLVR, Human T cell leukemia virus (I and II) receptor, member 1, MGC141895, MGC141896, PED, RATGTG1, Receptor for HTLV 1 and HTLV 2, SDCHCN, SLC2A, SLC2A1, Solute carrier family 2, Solute carrier family 2 (facilitated glucose transporter)
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Glut1 protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110748
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Glut1
Conjugation:
Unconjugated
Observed MW:
50-300 kDa
Calculated MW:
54 kDa
Recommended Dilution:
IHC 1:1000-5000; WB 1:10000-50000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P11166
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.