The Recombinant GRK2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331164) against GRK2. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IP applications. It has been validated by WB analysis of HL-60, U-2 OS, A431. The target is localized to the cytoplasm, membrane.