The Recombinant GSDME Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C333252) against GSDME. Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of U251MG, U2OS, HepG2, Hela. The target is localized to the cytosol, Plasma Membrane, other locations: membrane.