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Recombinant HIF1 beta Monoclonal Antibody (AGEL8656)

Datasheet MSDS
SKU AGEL8656
Product Type Antibody
Reactivity Human, Mouse, Rat, Hamster
Applications WB, IHC-P
Host Species Rabbit
Clonality Monoclonal
Clone C123351
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant HIF1 beta Monoclonal Antibody

The Recombinant HIF1 beta Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C123351) against HIF1 beta. Hypoxia-inducible factor 1 (HIF1) is a heterodimeric transcription factor that plays a critical role in the cellular response to hypoxia (1). The HIF1 complex consists of two subunits, HIF-1α and HIF-1β, which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family (2). HIF1 regulates the transcription of a broad range of genes that facilitate responses to the hypoxic environment, including genes regulating angiogenesis, erythropoiesis, cell cycle, metabolism and apoptosis. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse, Rat and Hamster samples.

This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of Hela, CHO-K1, C6, Ramos and IHC analysis of Human lung cancer. The target is localized to the nucleus.

Product Name:Recombinant HIF1 beta Monoclonal Antibody
SKU:AGEL8656
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:ARNT, ARNT protein, Aryl hydrocarbon receptor nuclear translocator, bHLHe2, Class E basic helix-loop-helix protein 2, Dioxin receptor, Dioxin receptor nuclear translocator, Drnt, HIF 1 beta, HIF 1beta, HIF-1-beta, HIF1-beta, HIF1B, HIF1beta, Hypoxia Inducible Fact, Hypoxia Inducible Factor 1, Hypoxia inducible factor 1 beta, Hypoxia-inducible factor 1-beta, nuclear translocator, Tango
Reactivity:Human, Mouse, Rat, Hamster
Immunogen:Recombinant protein of human HIF1 beta
Applications:WBIHC-P
Clonality:Recombinant Monoclonal
Clone No:C123351
Host:Rabbit
Isotype:Rabbit IgG
Target:HIF1 beta
Conjugation:Unconjugated
Observed MW:87 kDa
Calculated MW:87 kDa
Recommended Dilution:WB 1:500-1000; IHC 1:50-100
UniProt:P27540
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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