Description
Recombinant HLA-DPB1 Monoclonal Antibody
The Recombinant HLA-DPB1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C211174) against HLA-DPB1. Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Mouse samples.
This antibody is suitable for WB, IHC, IF and IP applications. It has been validated by WB analysis of Mouse spleen, Raji, IHC analysis of Human tonsil, IF analysis of Raji, Ramos and IP analysis of Raji cells extracts. The target is localized to the cytoplasm.
| Product Name: | Recombinant HLA-DPB1 Monoclonal Antibody |
| SKU: | AGEL6480 |
| Size: | 50 µL, 100 µL |
| Antibody Type: | Recombinant Monoclonal Antibody |
| Synonyms: | beta-1 subunit, class I, class II, D6S221E, DMA, DMB, DP beta, DP beta 1, DP beta 1 chain, DP(W4) beta chain, DPB, DPB 1, DPB1, DRB, H2Ea, HLA class II histocompatibility antigen, HLA class II histocompatibility antigen DM beta chain, HLA DMB, HLA DP1A, HLA DPB1, HLA SB alpha chain, HLA-A, HLA-A histocompatibility type, HLA-DP, HLA-DP histocompatibility type, HLA-DP1B, HLA-DPB, HLA-DPB1, HLADM, HLADP1B, HLASB, HLASB histocompatibility type, Human MHC class II HLA SB alpha, LA class II histocompatibility antigen DP alpha 1 chain, major histocompatibility complex, Major histocompatibility complex class II, Major histocompatibility complex class II DP alpha 1, Major histocompatibility complex class II DP beta 1, MHC class II antigen DMB, MHC class II antigen DPB1, MHC class II DP3 alpha, MHC class II DPA1, MHC class II HLA-DP-beta-1, MHC DPB1, MHC HLA DPB1, PLT1, Primed lymphocyte test 1, RING6, RING7 |
| Reactivity: | Human, Mouse |
| Immunogen: | Recombinant human HLA-DPB1 fragment |
| Applications: | WBIHCIFIP |
| Clonality: | Recombinant Monoclonal |
| Clone No: | C211174 |
| Host: | Rabbit |
| Isotype: | Rabbit IgG |
| Target: | HLA-DPB1 |
| Conjugation: | Unconjugated |
| Observed MW: | 29 kDa |
| Calculated MW: | 29 kDa |
| Recommended Dilution: | WB 1:500-1000; IHC 1:200-1000; IF 1:50; IP 1:50-100 |
| UniProt: | P04440 |
| Purification: | Protein A |
| Concentration: | 1 mg/mL |
| Buffer: | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Storage: | Store at -20°C valid for 12 months. Avoid freeze / thaw cycles. |