The Recombinant HNF-1B Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C131348) against HNF-1B. Hepatocyte nuclear factor 1-beta (HNF-1B) is a transcription factor which binds to specific regions of nucleic acid. HNF-1B, which plays critical roles in the regulation of glucose transport and metabolism, glucose-stimulated insulin secretion, and also in the embryonic development and later function of the pancreas, kidneys, genitourinary tract, liver, and the biliary tree. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of Jurkat, Mouse liver, Rat liver. The target is localized to the nucleus.