The Recombinant Hsf1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C323352) against Hsf1. The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of this gene. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of Hela, Jurkat and IHC analysis of Human breast cancer. The target is localized to the Cytoplasm. Nucleus. Cytoplasmic during normal growth. On activation, translocates to nuclear stress granules. Colocalizes with SUMO1 in nuclear stress granules.