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Recombinant HSP27 Monoclonal Antibody (AGEL6239)

Datasheet MSDS
SKU AGEL6239
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, IP, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C110933
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant HSP27 Monoclonal Antibody

The Recombinant HSP27 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110933) against HSP27. The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of Hela. The target is localized to the cytoplasm, nucleus, cytoplasm, cytoskeleton, spindle, Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.

Product Name:Recombinant HSP27 Monoclonal Antibody
SKU:AGEL6239
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:28 kDa heat shock protein, CMT2F, DKFZp586P1322, epididymis secretory protein Li 102, Estrogen regulated 24 kDa protein, Estrogen-regulated 24 kDa protein, Heat shock 25kDa protein 1, Heat shock 27 kDa protein, Heat shock 27kD protein 1, Heat shock 27kDa protein, Heat shock 27kDa protein 1, Heat shock 28kDa protein 1, Heat Shock Protein 27, Heat shock protein beta 1, Heat shock protein beta-1, heat shock protein family B (small) member 1, HEL-S, HEL-S-102, HMN2B, HS.76067, HSP, Hsp 25, HSP 27, Hsp 28, Hsp B1, Hsp25, HSP27, HSP28, HSPB, HSPB1, SRP, SRP27, Stress responsive protein 27, Stress-responsive protein 27
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant Human HSP27 protein
Applications:WBIHCIFIPELISA
Clonality:Recombinant Monoclonal
Clone No:C110933
Host:Rabbit
Isotype:Rabbit IgG
Target:HSP27
Conjugation:Unconjugated
Observed MW:27 kDa
Calculated MW:23 kDa
Recommended Dilution:IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:P04792
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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