Recombinant Human APOM Protein (His Tag) (RPES4499)

SKU:
RPES4499
€142

Description

ELISA Kit Technical Manual

Recombinant Human APOM Protein (His Tag)

Background:Apolipoprotein M is a secreted protein which belongs to the Lipocalin family. ApoM often presents in high density lipoprotein (HDL) and to a lesser extent in triglyceride-rich lipoproteins (TGRLP) and low density lipoproteins (LDL). The ApoM gene encoded protein is expressed in liver and kidney, secreted through the plasma membrane but remains membrane-bound. ApoM probably involved in lipid transport. ApoM can bind sphingosine-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. The expression of ApoM could be regulated by platelet activating factor (PAF), Transforming Growth Factors (TGF), Insulin-Like Growth factor (IGF) and Leptin.
Name:Recombinant Human APOM Protein (His Tag)
Size:10µg
Assay Genie SKU:RPES4499
Synonyms:Apolipoprotein M; Apo-M; ApoM; Protein G3a; APOM; G3A; NG20
Species:Human
Expression host:Human Cells
Sequence:Met1-Asn188
Accession:O95445
Mol Mass:22.29 kDa
AP Mol Mass:26 kDa
Tag:C-His
Purity:> 80% as determined by reducing SDS-PAGE.
Endotoxin:< 1.0 EU per ?g as determined by the LAL method.
Storage:Lyophilized protein should be stored at < -20'C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7? for 2-7 days.Aliquots of reconstituted samples are stable at < -20'C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Reconstitution:Please refer to the printed manual for detailed information.
UniProt Protein Function:APOM: Probably involved in lipid transport. Can bind sphingosine-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. Plasma protein. Expressed in liver and kidney. Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6p21.33

Cellular Component: integral to plasma membrane

Molecular Function:antioxidant activity; lipid transporter activity; phospholipid binding

Biological Process: cholesterol homeostasis; reverse cholesterol transport; response to glucose stimulus; cholesterol efflux; lipoprotein metabolic process

NCBI Summary:The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]
UniProt Code:O95445
NCBI GenInfo Identifier:17370872
NCBI Gene ID:55937
NCBI Accession:O95445.2
UniProt Secondary Accession:O95445,Q5SRP4, Q9P046, Q9UMP6, B0UX98,
UniProt Related Accession:O95445
Molecular Weight:188
NCBI Full Name:Apolipoprotein M
NCBI Synonym Full Names:apolipoprotein M
NCBI Official Symbol:APOM
NCBI Official Synonym Symbols:G3a; NG20; apo-M; HSPC336
NCBI Protein Information:apolipoprotein M; protein G3a; NG20-like protein; alternative name: G3a, NG20
UniProt Protein Name:Apolipoprotein M
UniProt Synonym Protein Names:Protein G3a
Protein Family:Apomucin
UniProt Gene Name:APOM
UniProt Entry Name:APOM_HUMAN
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Additional Information

Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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