Apolipoprotein M is a secreted protein which belongs to the Lipocalin family. ApoM often presents in high density lipoprotein (HDL) and to a lesser extent in triglyceride-rich lipoproteins (TGRLP) and low density lipoproteins (LDL). The ApoM gene encoded protein is expressed in liver and kidney; secreted through the plasma membrane but remains membrane-bound. ApoM probably involved in lipid transport. ApoM can bind sphingosine-1-phosphate; myristic acid; palmitic acid and stearic acid; retinol; all-trans-retinoic acid and 9-cis-retinoic acid. The expression of ApoM could be regulated by platelet activating factor (PAF); Transforming Growth Factors (TGF); Insulin-Like Growth factor (IGF) and Leptin.
Product Name:
Human APOM Recombinant Protein (RPES4499)
Product Code:
RPES4499
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Apolipoprotein M, Apo-M, ApoM, Protein G3a, APOM, G3A, NG20
Accession:
O95445
Sequence:
Met1-Asn188
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Apolipoprotein M is produced by our Mammalian expression system and the target gene encoding Met1-Asn188 is expressed with a 6His tag at the C-terminus.
Purity:
> 80% as determined by reducing SDS-PAGE.
Mol Mass:
22.29 kDa
AP Mol Mass:
26 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.2.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
