B cell maturation protein (BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain; as well as TACI. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain; a 23 aa transmembrane domain; and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development; function and regulation.
Product Name:
Human BCMA/TNFRSF17 Recombinant Protein (RPES4267)
Product Code:
RPES4267
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Tumor necrosis factor receptor superfamily member 17,TNFRSF17,B-cell maturation protein,CD269
Accession:
Q02223
Sequence:
Met1-Ala54
Fusion tag:
C-Fc
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human BCMA is produced by our Mammalian expression system and the target gene encoding Met1-Ala54 is expressed with a Fc tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
32.8 kDa
AP Mol Mass:
38-40 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS;pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
