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Human BCMA/TNFRSF17 Recombinant Protein (RPES4267)

SKU:
RPES4267
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Growth Factors & Cytokines
$235
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Description

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Human BCMA/TNFRSF17 Recombinant Protein

B cell maturation protein (BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain; as well as TACI. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain; a 23 aa transmembrane domain; and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development; function and regulation.