CD38; also called ADP-ribosyl cyclase; is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate; the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes; osteoclasts; and in cardiac; pancreatic; liver and kidney cells. Through its production of cyclic ADP-ribose; CD38 modulates calcium-mediated signal transduction in many types of cells; including neutrophils and pancreatic beta cells.
Product Name:
Human CD157/BST1 Recombinant Protein (RPES4750)
Product Code:
RPES4750
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
ADP-ribosyl cyclase 2, Cyclic ADP-ribose hydrolase 2, BST-1, Bone marrow stromal antigen 1, Bone marrow stromal cell antigen 1
Accession:
Q10588
Sequence:
Gly29-Lys292
Fusion tag:
C-Fc
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human BST1 is produced by our Mammalian expression system and the target gene encoding Gly29-Lys292 is expressed with a Fc tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
57.1 kDa
AP Mol Mass:
75 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
