Ferritin heavy polypeptide 1 (FTH1) is a ubiquitous intracellular iron storage protein that binds and stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is needed for iron homeostasis. After oxidation, iron is absorbed in the ferrous form and transformed to ferric hydroxides. Ferritin is made up of 24 subunits from both the light and heavy chains. It is a key protein that participates in the transfer of iron to cells and regulates iron uptake in capsule cells during kidney development. Ferritin subunit structure variation may influence iron absorption and release in various tissues. Ferritin protein deficiency can lead to a number of neurodegenerative diseases. This protein can be made by almost all living things, including algae, bacteria, higher plants, and animals. Human FTH Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human FTH Recombinant Protein (RPES3650)
Product Code:
RPES3650
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Ferritin heavy chain,FTH1,FTH,FTHL6,Ferritin H subunit,Cell proliferation-inducing gene 15 protein,FHC,HFE5,PIG15
Accession:
P02794
Sequence:
Met 1-Ser183
Fusion tag:
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Ferritin heavy chain is produced by our E.coli expression system and the target gene encoding Met1-Ser183 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
21.2 kDa
AP Mol Mass:
22 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
