Recombinant Human GSTp1 Protein (His Tag) (RPES8824)
Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins. Besides, it regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. It thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
Product Name:
Recombinant Human GSTp1 Protein (His Tag)
SKU:
RPES8824
Size:
20μg, 100μg, 500μg, 1mg
Species:
Human
Synonyms:
FAEES3, GST class-pi, GST3, GSTP1, GSTP1-1, Glutathione S-transferase P
Tag:
N-His
Sequence:
Tyr4-Gln210
Expression Host:
E.coli
Accession:
P09211
Purity:
> 95% as determined by reducing SDS-PAGE.
Endotoxin:
< 10 EU/mg of the protein as determined by the LAL method
Bio-Activity:
Not validated for activity
Form:
Lyophilized powder
Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Storage:
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
