Human IGF/IGF1 Recombinant Protein (RPES1582)
- SKU:
- RPES1582
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
system_update_altDatasheet
Human IGF/IGF1 Recombinant Protein
Insulin-like growth factor I (IGF1) is a member of the family of insulin-like growth factors that are structurally similar to proinsulin. Proteolytic digestion of inactivated precursor protein with N- and C-terminal propeptide regions results in the formation of mature IGFs. Human IGF-I is a protein that contains 70 amino acids and has a 94 percent similarity with mouse IGF1, and it is cross-species active. IGF1 binds IGF-1R; IGF-2R; and the insulin receptor and plays a key role in cell cycle progression; cell proliferation and tumor progression. IGF1 expression is controlled by growth hormone. Human IGF/IGF1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human IGF/IGF1 Recombinant Protein (RPES1582) |
| Product Code: | RPES1582 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Insulin-Like Growth Factor I, IGF-I, Mechano Growth Factor, MGF, Somatomedin-C, IGF1, IBP1 |
| Accession: | P05019 |
| Sequence: | Thr52-Ala118 |
| Fusion tag: | |
| Activity: | Measured in a serum-free cell proliferation assay using MCF?7 human breast cancer cells. The ED50 for this effect is 52.4 ng/ml. |
| Endotoxin: | <0.5 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Insulin-like Growth Factor I is produced by our E.coli expression system and the target gene encoding Thr52-Ala118 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 7.3 kDa |
| AP Mol Mass: | 9 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 300mM NaAc; pH 6.5. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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