Interleukin 10(IL10), also known as cytokine synthesis inhibitory factor (CSIF),is a secreted protein andbelongs to the IL-10 family. IL-10 is produced by a variety of activated hematopoietic cell types, as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts. IL-10 is an anti-inflammatory TH2 cytokinethat has a key function in inhibiting the host's immune response, preventing damage. Many T helper cells are inactivated by IL-10, which is suggested to act as a feedback loop that restricts macrophage and DC effector activities on T cells. STAT3 is activated by IL-10 through the IL-10 receptor (IL-10 R) after it has been released. IL-10 is a potent anti-inflammatory cytokine that has established itself as an important indicator for numerous diseases and ailments, as well as a therapeutic drug for several illnesses. High amounts of IL-10 are also present in viral infections that cause immunodeficiency, particularly retroviral infections. IL-10's immunosuppressive qualities suggest that it may be used in the treatment of organ transplant rejection. Human IL0/Interleukin0 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human IL0/Interleukin0 Recombinant Protein (RPES1347)
Recombinant Human Interleukin-10 is produced by our Mammalian expression system and the target gene encoding Ser19-Asn178 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
19.6 kDa
AP Mol Mass:
16 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
