Interleukin-2(IL-2) is an interleukin, a cytokine signaling molecule in the immune system; it belongs to the IL-2 family. It is a potent immunoregulatory lymphokine generated by T-cells in response to antigenic or mitogenic stimulation. T-cell proliferation and other fundamental functions that are necessary for the immune response are dependent on T-cell IL-2/IL-2R signaling. B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages, and oligodendrocytes are all affected by IL-2. Interleukin-2/IL-2 Recombinant Protein (E.coli) is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Interleukin-2/IL-2 Recombinant Protein (E.coli) (RPES4026)
Measured in a cell proliferation assay using CTLL?2 mouse cytotoxic T cells. The specific activity of Recombinant Human IL-2 is ?1-107 IU/mg.
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Interleukin-2 is produced by our E.coli expression system and the target gene encoding Ala21-Thr153 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
15.5 kDa
AP Mol Mass:
14 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 10mM sodium citrate; pH 4.0
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
