PRDX3/Peroxiredoxin 3 is a mitochondrial protein that functions as an antioxidant. PRDX3 is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and PRDX3 can help E. coli that lack the C22 subunit overcome alkylhydroperoxide resistance. The mouse and human genes are highly conserved, and they reside in syntenic chromosomal regions. PRDX3 are part of a family that controls cellular proliferation, differentiation, and antioxidant functions based on sequence comparisons with recently cloned mammalian homologs. PRDX3 can protect cells from oxidative stress and help them survive prostate cancer. On chromosomes 1, 3, 13, and 22, scientists have discovered additional pseudogenes. The protein PRDX3 is linked to two eye diseases: pre-descemet corneal dystrophy and fuchs' endothelial dystrophy. Reactive oxygen species (ROS) detoxification and cellular aging are linked processes. Human Peroxiredoxin-3/PRDX3 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human Peroxiredoxin-3/PRDX3 Recombinant Protein (RPES1703)
Product Code:
RPES1703
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Thioredoxin-Dependent Peroxide Reductase Mitochondrial, Antioxidant Protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog, PRDX3, AOP1
Accession:
P30048
Sequence:
Pro63-Gln256
Fusion tag:
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Peroxiredoxin-3 is produced by our E.coli expression system and the target gene encoding Pro63-Gln256 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
21.6 kDa
AP Mol Mass:
25 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM TrisHCl,pH8.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
