SUMO3 belongs to the SUMO protein family and operates like ubiquitin. Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polyer. Nevertheless unlike ubiquitin that targets proteins for degration; SUMO3 takes part in several cellular processess; such as nuclear transport; transcription regulation; apoptosis and protein stability. SUMO3 participates in amyloid beta generation and has a key role in the oneset or progression of Alzheimer's disease.
Product Name:
Human SUMO3/SMT3A Recombinant Protein (RPES5226)
Product Code:
RPES5226
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Small Ubiquitin-Related Modifier 3, SUMO-3, SMT3 Homolog 1, SUMO-2, Ubiquitin-Like Protein SMT3B, Smt3B, SUMO3, SMT3B, SMT3H1
Accession:
P55854
Sequence:
Met 1-Phe103
Fusion tag:
N-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Small Ubiquitin-Related Modifier 3 is produced by our E.coli expression system and the target gene encoding Met1-Phe103 is expressed with a 6His tag at the N-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
13.8 kDa
AP Mol Mass:
19 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.2.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
