The Recombinant IGF2R/CI-M6PR Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121481) against IGF2R/CI-M6PR. The HAP1 is a nuclear enzyme that apparently performs two distinct roles in the cellular defense against oxidative stress. One well-established role is in the repair of a variety of lesions induced in DNA either by spontaneous hydrolysis or by reactive oxygen species (ROS). This function has been characterized in great detail and the roles played by individual active site amino acid residues have been defined. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of HeLa, Jurkat, C6, NIH/3T3 and IHC analysis of Human thyroid cancer. The target is localized to the Golgi apparatus membrane.
Product Name:
Recombinant IGF2R/CI-M6PR Monoclonal Antibody
SKU:
AGEL6786
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
300 kDa mannose 6 phosphate receptor, 300 kDa mannose 6-phosphate receptor, cation independent, Cation independent mannose 6 phosphate receptor, cation-independent mannose-6-phosphate receptor, CD222, CD222 antigen, CI Man 6 P receptor, CI Man-6-P receptor, CI MPR, CI-M6PR, CI-MPR, CIMPR, IGF 2 receptor, IGF 2R, IGF II receptor, IGF-II receptor, IGF-IIR, IGF2 receptor, IGF2R, Insulin like growth factor 2 receptor, Insulin like growth factor II receptor, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, M6P R, M6P-R, M6P/IGF2 receptor, M6P/IGF2R, M6PR, mannose 6 phosphate receptor, MPR, MPR 300, MPR1, MPR300, MPRI
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant human IGF2R/CI-M6PR fragment
Applications:
WBIHC
Clonality:
Recombinant Monoclonal
Clone No:
C121481
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
IGF2R/CI-M6PR
Conjugation:
Unconjugated
Observed MW:
300 kDa
Calculated MW:
274 kDa
Recommended Dilution:
WB 1:500-1000; IHC 1:50-200
UniProt:
P11717
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.