The Recombinant IGFBP3 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331410) against IGFBP3. Insulin-like growth factor-binding protein 3 (IGFBP3) is a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of Human plasma. The target is localized to the secreted.
