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Recombinant IL-1RA/IL1RN Monoclonal Antibody (AGEL5378)

Datasheet MSDS
SKU AGEL5378
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, IP, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C110059
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant IL-1RA/IL1RN Monoclonal Antibody

The Recombinant IL-1RA/IL1RN Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110059) against IL1RN. disease:Genetic variation in IL1RN is associated with susceptibility to diabetic nephropathy [MIM:612628]; also called susceptibility to microvascular complications of diabetes type 4 (MVCD4). Diabetic nephropathy is a kidney disease and resultant kidney function impairment due to the long standing effects of diabetes on the microvasculature (glomerulus) of the kidney. Features include increased urine protein and declining kidney function., function:Inhibits the activity of IL-1 by binding to its receptor. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of A431, Hela, HepG2, MOLT-4, THP-1, Raw264.7 and IHC analysis of Human colon cancer. The target is localized to the secreted, cytoplasm.

Product Name:Recombinant IL-1RA/IL1RN Monoclonal Antibody
SKU:AGEL5378
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:Anakinra, DIRA, F630041P17Rik, ICIL 1RA, ICIL-1RA, ICIL1RA, IL-1ra, IL-1ra3, IL-1RN, IL1 inhibitor, IL1F, IL1F3, IL1RA, IL1RN, IL1RN (IL1F3), Interleukin 1 receptor antagonist, Interleukin-1 receptor antagonist protein, Intracellular IL 1 receptor antagonist type II, Intracellular interleukin 1 receptor antagonist (icIL 1ra), IRAP, MGC10430, MVCD, MVCD4, Type II interleukin 1 receptor antagonist
Reactivity:Human, Mouse, Rat
Immunogen:A synthetic peptide corresponding to the center region of the human IL1Ra / IL1RN.
Applications:WBIHCIFIPELISA
Clonality:Recombinant Monoclonal
Clone No:C110059
Host:Rabbit
Isotype:Rabbit IgG
Target:IL1RN
Conjugation:Unconjugated
Observed MW:20 kDa
Calculated MW:17 kDa
Recommended Dilution:IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:P18510, P25085, P25086
Purification:Protein A
Concentration:1 mg/mL
Buffer:0.2 µm filtered solution in PBS
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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