The Recombinant IL-1RA Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111533) against IL-1RA. The founding members of the interleukin-1 (IL-1) superfamily include pro-inflammatory cytokines IL-1α, IL-1β and IL-1 receptor antagonist (IL-1RA). At least six similar proteins have been recently identified, including a homolog of IL-1RA (IL1F5). IL-1a, IL-1b and IL-1RA are mainly expressed in macrophages, monocytes, and dendritic cells. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of Hela, K562, RAW264.7, Rat spleen and IHC analysis of Human esophagus. The target is localized to the cytoplasm, secreted.
Product Name:
Recombinant IL-1RA Monoclonal Antibody
SKU:
AGEL6838
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Anakinra, DIRA, F630041P17Rik, ICIL 1RA, ICIL-1RA, ICIL1RA, IL-1ra, IL-1ra3, IL-1RN, IL1 inhibitor, IL1F, IL1F3, IL1RA, IL1RN, IL1RN (IL1F3), Interleukin 1 receptor antagonist, Interleukin-1 receptor antagonist protein, Intracellular IL 1 receptor antagonist type II, Intracellular interleukin 1 receptor antagonist (icIL 1ra), IRAP, MGC10430, MVCD, MVCD4, Type II interleukin 1 receptor antagonist
Reactivity:
Human, Mouse, Rat
Immunogen:
The specific immunogen used to produce this antibody is proprietary information.
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C111533
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
IL-1RA
Conjugation:
Unconjugated
Observed MW:
20 kDa
Calculated MW:
17 kDa
Recommended Dilution:
WB 1:2000-10000; IHC 1:200-1000; IF 1:200-1000; IP 1:50-200; ELISA 1:5000-20000
UniProt:
P18510, P25085, P25086
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.