The Recombinant IRE1α Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110967) against IRE1α. The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of LnCap. The target is localized to the endoplasmic reticulum membrane.
Product Name:
Recombinant IRE1α Monoclonal Antibody
SKU:
AGEL6273
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
ERN, ERN1, hIRE1p, IRE, IRE1, IRE1a, IRE1P
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human IRE1α protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110967
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
IRE1α
Conjugation:
Unconjugated
Observed MW:
110 kDa
Calculated MW:
110 kDa
Recommended Dilution:
IHC 1:100-500; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
O75460
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.