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Recombinant MASH1 Monoclonal Antibody (AGEL6924)

Datasheet MSDS
SKU AGEL6924
Product Type Antibody
Reactivity Human
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C331619
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant MASH1 Monoclonal Antibody

The Recombinant MASH1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331619) against MASH1. MASH1, also known as achaete-scute homolog 1 (ASCL1), is a basic helix-loop-helix (BHLH) transcription factor which plays an essential role in the differentiation of neuroendocrine cells and neural tissues. MASH1 directly binds the E-box motif (5'-CANNTG-3') on promoters, with dimerization with other BHLH proteins required for efficient DNA binding. Acting as a pioneer transcription factor, MASH1 also accesses closed chromatin, allowing other factors to promote transcription of neuronal genes and activate neural pathways. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of U-2 OS (negative?control),?SK-N-BE (2), IMR-32. The target is localized to the nucleus.

Product Name:Recombinant MASH1 Monoclonal Antibody
SKU:AGEL6924
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:Achaete scute complex homolog 1, Achaete scute complex homolog like 1, Achaete scute complex homologue 1, Achaete scute complex homologue like 1, Achaete scute complex like 1, Achaete scute family bHLH transcription factor 1, Achaete scute protein, Achaete-scute homolog 1, ASCL, Ascl 1, ASCL1, ASH, Ash 1, ASH-1, ASH1, bHLHa, bHLHa46, Class A basic helix-loop-helix protein 46, HASH, Hash 1, HASH1, Mammalian achaete scute homolog 1, Mammalian achaete scute homologue 1, MASH, Mash 1, MASH1
Reactivity:Human
Immunogen:Peptide. This information is proprietary to PTMab
Applications:WB
Clonality:Recombinant Monoclonal
Clone No:C331619
Host:Rabbit
Isotype:Rabbit IgG
Target:MASH1
Conjugation:Unconjugated
Observed MW:30 kDa
Calculated MW:25 kDa
Recommended Dilution:WB 1:1000
UniProt:P50553
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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