The Recombinant MBD2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111526) against MBD2. MBD2, also named as DMTase, binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. MBD2 binds hemi-methylated DNA as well. It recruits histone deacetylases and DNA methyltransferases. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, ICC/IF, FC and IP applications. It has been validated by WB analysis of C6, 3T3, HeLa, Rat brain, IHC analysis of Human tonsil and IF analysis of HL-60, HeLa. The target is localized to the nucleus.
Product Name:
Recombinant MBD2 Monoclonal Antibody
SKU:
AGEL6831
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
DKFZp586O0821, DMTase, MBD, MBD2, NY-CO, NY-CO-41
Reactivity:
Human, Mouse, Rat
Immunogen:
A synthetic peptide of human MBD2
Applications:
WBIHCICC/IFFCIP
Clonality:
Recombinant Monoclonal
Clone No:
C111526
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
MBD2
Conjugation:
Unconjugated
Observed MW:
43 kDa
Calculated MW:
43 kDa
Recommended Dilution:
WB 1:1000; IHC 1:20-500; ICC/IF 1:100; IP 1:20; FCM 1:20
UniProt:
Q9UBB5
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.