Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, but the function of granzyme D is unknown. Previous studies reported that granzyme D is developmentally regulated during pregnancy together with granzymes E, F, and G in granulated metrial gland cells and is upregulated by IL-2 and IL-15. Granzyme D was also suggested to have a role in stromal cell-lymphocyte interactions.
Product Name:
Mouse Granzyme D/GZMD Recombinant Protein (RPES0975)
Product Code:
RPES0975
Size:
10µg
Species:
Mouse
Expressed Host:
Human Cells
Synonyms:
Granzyme D, Gzmd
Accession:
P11033
Sequence:
Ile21-Leu252
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse Granzyme D is produced by our Mammalian expression system and the target gene encoding Ile21-Leu252 is expressed with a 6His tag at the C-terminus.
Purity:
> 90 % as determined by SDS-PAGE
Mol Mass:
26.8 kDa
AP Mol Mass:
80-90 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM HEPES, 150mM NaCl, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
