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Key Features

Recombinant MRE11 Monoclonal Antibody (AGEL6197)

Datasheet MSDS
SKU AGEL6197
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C110891
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant MRE11 Monoclonal Antibody

The Recombinant MRE11 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110891) against MRE11. This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by IHC analysis of Human cervical carcinoma. The target is localized to the nucleus, chromosome, telomere, chromosome, localizes to discrete nuclear foci after treatment with genotoxic agents.

Product Name:Recombinant MRE11 Monoclonal Antibody
SKU:AGEL6197
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:AT like disease, Ataxia telangiectasia disorder like, ATLD, DNA recombination and repair protein, Double strand break repair protein MRE11A, Double-strand break repair protein MRE11A, endo/exonuclease Mre11, HNGS, HNGS1, meiotic recombination (S. cerevisiae) 11 homolog A, Meiotic recombination 11 homolog 1, Meiotic recombination 11 homolog A, meiotic recombination 11 homolog A (S. cerevisiae), MmMRE11A, MRE, Mre 11, MRE 11a, MRE 11b, MRE11, MRE11 homolog 1, MRE11 homolog A, MRE11 homolog double strand break repair nuclease, MRE11 meiotic recombination 11 homolog A, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11A, MRE11B, OTTHUMP00000236830, OTTHUMP00000236831, OTTHUMP00000236832, OTTHUMP00000236833
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant Human MRE11 protein
Applications:WBIHCIFELISA
Clonality:Recombinant Monoclonal
Clone No:C110891
Host:Rabbit
Isotype:Rabbit IgG
Target:MRE11
Conjugation:Unconjugated
Recommended Dilution:IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:P49959
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Product ImageImmunohistochemistry of paraffin-embedded human cervical carcinoma using Recombinant MRE11 Monoclonal Antibody at dilution of 1:200.
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