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Key Features

Recombinant MSH2 Monoclonal Antibody (AGEL6532)

Datasheet MSDS
SKU AGEL6532
Product Type Antibody
Reactivity Human
Applications WB, IHC, IF, IP
Host Species Rabbit
Clonality Monoclonal
Clone C311227
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant MSH2 Monoclonal Antibody

The Recombinant MSH2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C311227) against MSH2. This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB, IHC, IF and IP applications. It has been validated by WB analysis of HeLa, IHC analysis of Human esophagus, Human tonsil, IF analysis of HeLa and IP analysis of HeLa cells extracts. The target is localized to the nucleus.

Product Name:Recombinant MSH2 Monoclonal Antibody
SKU:AGEL6532
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:COCA, COCA1, FCC, FCC1, HNPCC, HNPCC1, LCFS, LCFS2, MSH, MSH2, mutS homolog, mutS homolog 2
Reactivity:Human
Immunogen:Recombinant human MSH2 fragment
Applications:WBIHCIFIP
Clonality:Recombinant Monoclonal
Clone No:C311227
Host:Rabbit
Isotype:Rabbit IgG
Target:MSH2
Conjugation:Unconjugated
Observed MW:104 kDa
Calculated MW:105 kDa
Recommended Dilution:WB 1:500-1000; IHC 1:50; IF 1:50-100; IP 1:50-100
UniProt:P43246
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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