The Recombinant MTAP Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C221429) against MTAP. MTAP is an enzyme essential for the salvage pathway for both adenine and methionine synthesis. MTAP catalyzes the cleavage of 5’-methylthioadenosine into adenine and 5-methylthio-D-ribose-1-phosphate. Adenine is then used to generate AMP whereas 5-methylthio-D-ribose-1-phosphate is converted into methionine. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Mouse samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of A549 (Negative control), HT-29, HeLa, NIH/3T3 and IHC analysis of Human breast. The target is localized to the cytoplasm, nucleus.
Product Name:
Recombinant MTAP Monoclonal Antibody
SKU:
AGEL6734
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
5' methylthioadenosine phosphorylase, 5''-methylthioadenosine phosphorylase, BDMF, c86fus, DMSFH, DMSMFH, Epididymis luminal protein 249, HEL, HEL 249, HEL-249, LGMBF, MeSAdo phosphorylase, Methylthioadenosine phosphorylase, MSAP, MTA phosphorylase, MTAP, MTAPase, S methyl 5 thioadenosine phosphorylase, S methyl 5' thioadenosine phosphorylase, S-methyl-5''-thioadenosine phosphorylase
Reactivity:
Human, Mouse
Immunogen:
Recombinant human MTAP fragment
Applications:
WBIHC
Clonality:
Recombinant Monoclonal
Clone No:
C221429
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
MTAP
Conjugation:
Unconjugated
Observed MW:
31 kDa
Calculated MW:
31 kDa
Recommended Dilution:
WB 1:1000-3000; IHC 1:50-100
UniProt:
Q13126
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.