The Recombinant mtTFA Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C313370) against mtTFA. This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IHC-P and IF applications. It has been validated by WB analysis of K562, Hela and IF analysis of Human breast cancer, Hela. The target is localized to the mitochondrion.