The Recombinant MX1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110256) against MX1. This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of A549. The target is localized to the cytoplasm, endoplasmic reticulum membrane, peripheral membrane protein, Cytoplasmic side. Cytoplasm, perinuclear region, Binds preferentially to negatively charged phospholipids (PubMed:21900240). Colocalizes with CCHFV protein N in the perinuclear region (PubMed:15047845), cytoplasm, nucleus, Translocates into the nuclei of HSV-1 infected cells (PubMed:20603636).
Product Name:
Recombinant MX1 Monoclonal Antibody
SKU:
AGEL5575
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
MX1
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human MX1 protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110256
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
MX1
Conjugation:
Unconjugated
Observed MW:
76 kDa
Calculated MW:
76 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
P20591
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
