The Recombinant N-Myc Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331655) against N-Myc. Members of the Myc/Max/Mad network function as transcriptional regulators with roles in various aspects of cell behavior, including proliferation, differentiation, and apoptosis. These proteins share a common basic-helix-loop-helix leucine zipper (bHLH-ZIP) motif required for dimerization and DNA-binding. Max was originally discovered based on its ability to associate with c-Myc and found to be required for the ability of Myc to bind DNA and activate transcription. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of HeLa (negative control), IMR-32. The target is localized to the nucleus.
Product Name:
Recombinant N-Myc Monoclonal Antibody
SKU:
AGEL6960
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
bHLHe, bHLHe37, Class E basic helix-loop-helix protein 37, MODED, MYCN, N myc, N myc proto oncogene protein, N-myc, N-myc proto-oncogene protein, Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene, Neuroblastoma MYC oncogene, NMYC, NMYC proto oncogene protein, ODED, Oncogene NMYC, pp65/67, V myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog, v myc avian myelocytomatosis viral related oncogene neuroblastoma derived, v myc myelocytomatosis viral related oncogene neuroblastoma derived
Reactivity:
Human
Immunogen:
Peptide. This information is proprietary to PTMab.
Applications:
WB
Clonality:
Recombinant Monoclonal
Clone No:
C331655
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
N-Myc
Conjugation:
Unconjugated
Observed MW:
62 kDa
Calculated MW:
50 kDa
Recommended Dilution:
WB 1:50000
UniProt:
P04198
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Western Blot with N-Myc Monoclonal Antibody at dilution of 1:1000. Lane 1: HeLa (negative control), Lane 2: IMR- 32 Observed-MW:62 kDa Calculated-MW:50 kDa
