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Key Features

Recombinant NEDD4 Monoclonal Antibody (AGEL8676)

Datasheet MSDS
SKU AGEL8676
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C133371
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant NEDD4 Monoclonal Antibody

The Recombinant NEDD4 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C133371) against NEDD4. This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of Hela, A549, HL-60, U2OS, U87-MG.

Product Name:Recombinant NEDD4 Monoclonal Antibody
SKU:AGEL8676
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:NEDD4, NEDD4-1, RPF1
Reactivity:Human, Mouse, Rat
Immunogen:A synthetic peptide of human NEDD4
Applications:WB
Clonality:Recombinant Monoclonal
Clone No:C133371
Host:Rabbit
Isotype:Rabbit IgG
Target:NEDD4
Conjugation:Unconjugated
Observed MW:115 kDa
Calculated MW:149 kDa
Recommended Dilution:WB 1:2000-3000
UniProt:P46934
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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