The Recombinant NPM1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111235) against NPM1. Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and FCM applications. It has been validated by WB analysis of HeLa, Jurkat, MCF-7, NIH/3T3, PC-12, IHC analysis of Human liver, Mouse pancreas, Rat spleen, IF analysis of MCF-7, NIH/3T3 and FCM analysis of Hela. The target is localized to the nucleus.
Product Name:
Recombinant NPM1 Monoclonal Antibody
SKU:
AGEL6540
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
B23, NPM, NPM1
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant human NPM1 fragment
Applications:
WBIHCIFFCM
Clonality:
Recombinant Monoclonal
Clone No:
C111235
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
NPM1
Conjugation:
Unconjugated
Observed MW:
37 kDa
Calculated MW:
33 kDa
Recommended Dilution:
WB 1:500-2000; IHC 1:200-1000; IF 1:100-500; FCM 1:50-100
UniProt:
P06748
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
