The Recombinant Nrf1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C113374) against Nrf1. This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P and IF applications. It has been validated by WB analysis of C6, 3T3, Hela and IF analysis of Human colon cancer, Hela. The target is localized to the nucleus.
Product Name:
Recombinant Nrf1 Monoclonal Antibody
SKU:
AGEL8679
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
alpha pal, alpha palindromic binding protein, Alpha palindromic-binding protein, Alpha-pal, locus control region factor 1, NFE2 related factor 1, NRF-1, NRF1, Nuclear respiratory factor 1