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Key Features

Recombinant Nucleolin Monoclonal Antibody (AGEL6926)

Datasheet MSDS
SKU AGEL6926
Product Type Antibody
Reactivity Human, Rat, Mouse
Applications WB, IHC
Host Species Rabbit
Clonality Monoclonal
Clone C121621
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant Nucleolin Monoclonal Antibody

The Recombinant Nucleolin Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121621) against Nucleolin. Nucleolin is a multi-functional protein that is one of the major components of the nucleoli. Nucleolin plays an essential role in various steps of ribosome biogenesis including rRNA synthesis, processing of pre-rRNA, pre-ribosomal RNA assembly, and transport of ribosomal proteins out of the nucleus. Down regulation of nucleolin leads to increased expression of p53, defects in genome duplication, and a delay at prometaphase during mitosis leading to cell cycle arrest. In addition, nucleolin has been found in a complex with Rad51 and may participate in DNA repair by homologous recombination. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of MDA-MB-231,?MCF-7, K562 and IHC analysis of Human colon, Human breast cancer, Mouse cerebrum, Rat cerebrum. The target is localized to the cytoplasm, nucleus.

Product Name:Recombinant Nucleolin Monoclonal Antibody
SKU:AGEL6926
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:C23, NCL, Nsr, Nsr1, nucleolin
Reactivity:Human, Mouse, Rat
Immunogen:Peptide. This information is proprietary to PTMab.
Applications:WBIHC
Clonality:Recombinant Monoclonal
Clone No:C121621
Host:Rabbit
Isotype:Rabbit IgG
Target:Nucleolin
Conjugation:Unconjugated
Observed MW:110 kDa
Calculated MW:77 kDa
Recommended Dilution:WB 1:100000-1000000; IHC 1:50
UniProt:P19338
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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