The Recombinant ORAI3 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331438) against ORAI3. ORAI3, also named as TMEM142C, is a key regulator or component of store-operated Ca2+ channel and transcription factor NFAT nuclear import. ORAI3 channels appeared to differ from Orai1 and -2 in being somewhat resistant to the process of Ca2+ depotentiation. Diseases associated with ORAI3 include Estrogen-Receptor negative breast cancer and T Cell and NK Cell Immunodeficiency. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of A431, A549, Raji, NIH/3T3. The target is localized to the membrane.
Product Name:
Recombinant ORAI3 Monoclonal Antibody
SKU:
AGEL6743
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
ORAI, ORAI3, TMEM142C
Reactivity:
Human
Immunogen:
Recombinant human ORAI3 fragment
Applications:
WB
Clonality:
Recombinant Monoclonal
Clone No:
C331438
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
ORAI3
Conjugation:
Unconjugated
Observed MW:
32 kDa
Calculated MW:
32 kDa
Recommended Dilution:
WB 1:500-1000
UniProt:
Q9BRQ5
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
![Anti-ORAI3 [R06-8B3] Monoclonal Antibody (AGMB00319)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/271608/693405/anti-orai3-r06-8b3-monoclonal-antibody-agmb00319__13938.1774509207.jpg?c=2 "Anti-ORAI3 [R06-8B3] Monoclonal Antibody (AGMB00319)")
