The Recombinant PDE1B Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C120853) against PDE1B. The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of HeLa. The target is localized to the cytoplasm, cytosol.
Product Name:
Recombinant PDE1B Monoclonal Antibody
SKU:
AGEL6159
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
HEL-S-79p, PDE1B, PDE1B1, PDES1B
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human PDE1B protein
Applications:
WBIHC
Clonality:
Recombinant Monoclonal
Clone No:
C120853
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
PDE1B
Conjugation:
Unconjugated
Observed MW:
59 kDa
Calculated MW:
59 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:1000-5000
UniProt:
Q01064
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Western Blot with Recombinant PDE1B Monoclonal Antibody at dilution of 1:1000 dilution. Lane A: HeLa lysate. Observed-MW:59 kDa Calculated-MW:59 kDa
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