The Recombinant PF4 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C321390) against PF4. Platelet factor 4(encoded by PF4) is a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of Human platelets and IHC analysis of Human spleen. The target is localized to the secreted.
