The Recombinant Phospho-Stat6 (Tyr641) Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C120063) against Stat6 (Tyr641). The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P, FC and IP applications. It has been validated by WB analysis of Hela, Raw264.7 and IHC analysis of Mouse lung. The target is localized to the cytoplasm, nucleus.
12S1644, D12S, D12S1644, IL 4 STAT, IL-4 Stat, IL-4-STAT, IL4 STAT, Interleukin 4 Induced, Interleukin 4 Induced Transcription Factor IL4 STAT, interleukin4 induced, Signal Transducer and Activator of Transcription, Signal Transducer and Activator of Transcription 6, Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced, Signal Transducer And Activator Of Transcription 6 Nirs Variant 1, STAT, STAT 6, STAT interleukin4 induced, STAT6, STAT6B, STAT6C, Transcription factor IL 4 STAT
Reactivity:
Human, Mouse, Rat
Immunogen:
A synthetic phosphopeptide corresponding to residues around Tyr641 of the Human Stat6
