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Key Features

Recombinant PMS2 Monoclonal Antibody (AGEL6308)

Datasheet MSDS
SKU AGEL6308
Product Type Antibody
Reactivity Human
Applications WB, IHC, IF, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C311002
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant PMS2 Monoclonal Antibody

The Recombinant PMS2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C311002) against PMS2. The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer. The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers, and is necessary for removal of the mismatched DNA. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of Hela. The target is localized to the nuclear.

Product Name:Recombinant PMS2 Monoclonal Antibody
SKU:AGEL6308
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:HNPCC, HNPCC4, MLH, MLH4, PMS, PMS2, PMS2CL, PMSL, PMSL2
Reactivity:Human
Immunogen:Recombinant Human PMS2 protein
Applications:WBIHCIFELISA
Clonality:Recombinant Monoclonal
Clone No:C311002
Host:Rabbit
Isotype:Rabbit IgG
Target:PMS2
Conjugation:Unconjugated
Observed MW:110 kDa
Calculated MW:96 kDa
Recommended Dilution:IHC 1:200-1000; WB 1:500-5000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:P54278
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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