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Recombinant PP1C beta Monoclonal Antibody (AGEL8689)

Datasheet MSDS
SKU AGEL8689
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC-P, IF
Host Species Rabbit
Clonality Monoclonal
Clone C113384
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant PP1C beta Monoclonal Antibody

The Recombinant PP1C beta Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C113384) against PP1C beta. The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC-P and IF applications. It has been validated by WB analysis of K562, Rat Rat Brain, C6, 3T3, Hela and IF analysis of Human colon cancer, Hela. The target is localized to the Cytoplasm. Nucleus. Nucleus, nucleoplasm. nucleus, nucleolus. Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles.

Product Name:Recombinant PP1C beta Monoclonal Antibody
SKU:AGEL8689
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:beta isozyme, catalytic subunit, de, delta isoform, MGC3672, PP 1B, PP-1B, PP1B, PP1beta, PPP1CB, PPP1CD, Protein phosphatase 1, Protein phosphatase 1 beta, Protein phosphatase 1 catalytic subunit beta isoform, Protein phosphatase 1 delta, Serine threonine protein phosphatase PP1 beta catalytic subunit, Serine/threonine-protein phosphatase PP1-beta catalytic subunit
Reactivity:Human, Mouse, Rat
Immunogen:A synthetic peptide of human PPP1CB
Applications:WBIHC-PIF
Clonality:Recombinant Monoclonal
Clone No:C113384
Host:Rabbit
Isotype:Rabbit IgG
Target:PP1C beta
Conjugation:Unconjugated
Observed MW:37 kDa
Calculated MW:37 kDa
Recommended Dilution:WB 1:1000-3000; IHC 1:50-100; IF 1:50-100
UniProt:P62140
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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