The Recombinant PRK2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C131425) against PRK2. PRK2 is a member of the protein kinase C-related kinases (PRKs), a subfamily of Ser/Thr-specific kinases with a catalytic domain highly homologous to the PKC family. PKC-related serine/threonine-protein kinase and Rho/Rac effector protein participate in specific signal transduction responses in the cell. PRK2 plays a role in regulating cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion, and transcription activation signaling processes. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of 293T, HeLa, HepG2, NIH/3T3, PC-12. The target is localized to the nucleus, cytoplasm, cytoskeleton.