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Recombinant PRMT5 Monoclonal Antibody (AGEL6563)

Datasheet MSDS
SKU AGEL6563
Product Type Antibody
Reactivity Human
Applications WB, IHC, IP
Host Species Rabbit
Clonality Monoclonal
Clone C321258
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant PRMT5 Monoclonal Antibody

The Recombinant PRMT5 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C321258) against PRMT5. Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H and may regulate its transcriptional elongation properties. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB, IHC and IP applications. It has been validated by WB analysis of HeLa, HEK-293, MCF7, HepG2, IHC analysis of Human breast cancer, Human liver cancer and IP analysis of MCF7 cells extracts. The target is localized to the chromosome, cytoplasm, Golgi apparatus, nucleus.

Product Name:Recombinant PRMT5 Monoclonal Antibody
SKU:AGEL6563
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:72 kDa ICln binding protein, 72 kDa ICln-binding protein, ANM5, Histone synthetic lethal 7, Histone-arginine N-methyltransferase PRMT5, HMT1 hnRNP methyltransferase like 5, homolog of, HRMT1L, HRMT1L5, IBP, IBP72, Jak-binding protein 1, JBP, JBP 1, JBP1, PRMT, PRMT 5, PRMT5, Protein arginine methyltransferase 5, Protein arginine N methyltransferase 5, Protein arginine N methyltransferase 5 N terminally processed, Protein arginine N-methyltransferase 5, S. cerevisiae, S. POMBE, S. POMBE HOMOLOG OF, SHK1 KINASE BINDING PROTEIN 1, Shk1 kinase binding protein 1 homolog, Shk1 kinase-binding protein 1 homolog, Shk1 kinase/binding protein 1, SKB, SKB 1, SKB1, SKB1 homolog, SKB1: SKB1 homolog (S. pombe), SKB1Hs
Reactivity:Human
Immunogen:Recombinant human PRMT5 fragment
Applications:WBIHCIP
Clonality:Recombinant Monoclonal
Clone No:C321258
Host:Rabbit
Isotype:Rabbit IgG
Target:PRMT5
Conjugation:Unconjugated
Observed MW:70 kDa
Calculated MW:73 kDa
Recommended Dilution:WB 1:2000-10000; IHC 1:50-100; IP 1:25-50
UniProt:O14744
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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